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Pancreatic Neoplasms: HELP
Articles by Yihua Zhou
Based on 5 articles published since 2010
(Why 5 articles?)
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Between 2010 and 2020, Yihua Zhou wrote the following 5 articles about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Review Synchronous Pancreatic Ductal Adenocarcinoma and Hepatocellular Carcinoma: Report of a Case and Review of the Literature. 2018

Lai, Jenny Z / Zhou, Yihua / Cao, Dengfeng. ·University College, Washington University in St. Louis, St. Louis, MO, U.S.A. · Department of Pathology and Immunology, Washington University in Saint Louis School of Medicine, St. Louis, MO, U.S.A. · Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, U.S.A. · Department of Pathology and Immunology, Washington University in Saint Louis School of Medicine, St. Louis, MO, U.S.A. dengfengcao@wustl.edu. ·Anticancer Res · Pubmed #29715132.

ABSTRACT: Two or more histologically distinct malignancies diagnosed during the same hospital admission are uncommon, but they do exist. Cases with synchronous primary pancreatic ductal adenocarcinoma and hepatocellular carcinoma are rarely seen. This is a case report of a 56 years old Caucasian female with the chief complaint of jaundice over a duration of 10 days. CT imaging findings revealed a 3.5 cm ill-defined pancreatic head mass and a 1.5 cm liver mass in the segment 5. EUS-FNA cytology showed pancreatic head ductal adenocarcinoma (PDAC). Liver biopsy revealed a well differentiated hepatocellular carcinoma (HCC). The patient underwent a pancreaticoduodenectomy and the pathology revealed a pancreatic ductal adenocarcinoma extending into peripancreatic soft tissue, portal vein and vascular groove with perineural invasion. This is a unique and challenging case with the coexistence of a primary PDAC and a primary HCC. To the best of our knowledge, this is the first documented case of synchronous PDAC and HCC in the English literature. The diagnosis and treatment of the two entities are discussed.

2 Article Hepatic Collision Tumor of Metastatic Pancreatic Adenocarcinoma and Chronic Lymphocytic Leukemia: A Case Report. 2018

Al-Taee, Ahmad / Lai, Jinping / Chen, Yongxin / Zhou, Yihua / Jallad, Bassel. ·Department of Internal Medicine, Saint Louis University, St Louis, MO, USA. · Department of Pathology, Saint Louis University, St Louis, MO, USA. · Department of Radiology, Saint Louis University, St Louis, MO, USA. · Division of Hematology and Oncology, Department of Internal Medicine, Saint Louis University Cancer Center, 3655 Vista Avenue, St Louis, MO, 63110, USA. jalladbm@slu.edu. ·J Gastrointest Cancer · Pubmed #27868155.

ABSTRACT: -- No abstract --

3 Article Pancreatic Mucinous Cystic Neoplasm Communicating with Main Pancreatic Duct: An Unrecognized Presentation of Pancreatic Mucinous Neoplasm? 2017

Zhou, Weixun / Saam, Trustin / Zhou, Yihua / Trevino, Jose / Liu, Xiuli / Cao, Dengfeng / Lai, Jinping. ·Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, P.R. China. · Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A. · Department of Radiology, Saint Louis University School of Medicine, St. Louis, MO, U.S.A. · Department of Surgery, University of Florida College of Medicine, Gainesville, FL, U.S.A. · Department of Pathology, Immunology, and Laboratory Medicine, Washington University in Saint Louis, St. Louis, MO, U.S.A. · Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A. jinpinglai@ufl.edu. ·Anticancer Res · Pubmed #29187489.

ABSTRACT: Mucinous cystic neoplasms (MCNs) and intraductal papillary mucinous neoplasms (IPMNs) are two well recognized entities of precursor cystic lesions of pancreatic duct adenocarcinoma. The characteristic features of MCNs are the lined mucinous epithelium with underlying ovarian-type stroma, but without communication with the ducts, while that for IPMNs are the communication with the ducts but without the underlying ovarian-type stroma. Here we report a case of MCN communicating with the main pancreatic duct in a 68-year-old woman. The initial radiographic diagnosis was pancreatic IPMN with main pancreatic involvement and this was also confirmed during gross examination. Histologically, the pancreatic cystic neoplasm was lined with mucinous epithelium with underlying ovarian-type of stroma. Immunohistochemical stains confirmed that the stroma cells were positive for ER, PR, alpha-inhibin and focally positive for CD10. The final pathologic diagnosis was pancreatic mucinous cystic neoplasm communicating with the main pancreatic duct. To the best of our knowledge, this is the second pathology confirmed case of MCN communicating with the main pancreatic duct. A careful gross examination and bivalvation of the main duct communicating with the cystic neoplasm helps render the correct diagnosis. If more cases are reported in the future, the MCN communicating with duct could become a new entity of pancreatic mucinous neoplasm.

4 Article Comparison of endoscopic ultrasound guided fine needle aspiration and PET/CT in preoperative diagnosis of pancreatic adenocarcinoma. 2017

Lai, Jin-Ping / Yue, Yong / Zhang, Wei / Zhou, Yihua / Frishberg, David / Jamil, Laith H / Mirocha, James M / Guindi, Maha / Balzer, Bonnie / Bose, Shikha / Cao, Dengfeng / Lo, Simon / Fan, Xuemo / Rutgers, Joanne K. ·Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Pathology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. Electronic address: jinpinglai@ufl.edu. · Department of Radiation Oncology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. · Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. · Department of Radiology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA. · Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. · Division of Gastroenterology and Hepatology, Digestive Disease Center, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. · Biostatistics Core, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. · Department of Pathology, Immunology and Laboratory Medicine, Washington University in St. Louis, St. Louis, MO 63130, USA. · Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: RutgersJK@cshs.org. ·Pancreatology · Pubmed #28501471.

ABSTRACT: BACKGROUND: Endoscopic ultrasound guided fine needle aspiration (EUS-FNA) is the procedure of choice to investigate and sample pancreatic masses for the preoperative diagnosis of pancreatic ductal adenocarcinoma (PDAC). The role of METHODS: Preoperative evaluation by PET/CT and EUS-FNA was performed on 25 patients with pancreatic solid lesions, who underwent a subsequent Whipple procedure or partial pancreatic resection. RESULTS: This series included 19 PDACs and 6 non-PDACs including 1 metastatic breast ductal adenocarcinoma, 2 low grade neuroendocrine tumors, 2 chronic pancreatitis and 1 gastrointestinal tumor abutting the pancreas. EUS-FNA correctly diagnosed 18 of 19 PDACs, 1 metastatic breast ductal adenocarcinoma and all 5 of the other non-PDAC cases. One case of well differentiated PDAC was negative on EUS-FNA. PET/CT provided excellent size and was positive in 14 of 19 PDACs and the metastatic breast ductal adenocarcinoma. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy for EUS-FNA in diagnosis of selected pancreatic tumors were 91%, 100%, 100%, 50% and 92%, respectively, while they were 65%, 100%, 100%, 20% and 68% for PET/CT, respectively. CONCLUSIONS: Compared to PET/CT, EUS-FNA has a higher sensitivity and accuracy for preoperative diagnosis of PDAC. However, PET/CT provides excellent size, volume and stage information. A combination of both PET/CT and EUS will better help guide diagnosis and treatment of pancreatic adenocarcinoma.

5 Article Primary Angiosarcoma of the Pancreas. 2017

Meeks, Marshall / Grace, Shane / Veerapong, Jula / Chen, Yongxin / Cao, Dengfeng / Zhou, Yihua / Lai, Jin-Ping. ·Department of Pathology, Saint Louis University School of Medicine, 1402 S. Grand Blvd, St Louis, MO, 63104, USA. · Department of Surgery, Saint Louis University School of Medicine, Saint Louis, MO, USA. · Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA. · Department of Radiology, Saint Louis University School of Medicine, Saint Louis, MO, USA. · Department of Pathology, Saint Louis University School of Medicine, 1402 S. Grand Blvd, St Louis, MO, 63104, USA. jinpinglai@slu.edu. ·J Gastrointest Cancer · Pubmed #27228987.

ABSTRACT: -- No abstract --