Vincenzi, Matteo / Pasquotti, Giulio / Polverosi, Roberta / Pasquali, Claudio / Pomerri, Fabio. · ·Cancer Imaging · Pubmed #25609358.

ABSTRACT: BACKGROUND: To describe the main imaging characteristics of pancreatic metastases from renal cell carcinoma (RCC) with particular attention to CT features, underlining possible criteria for a differential diagnosis. METHODS: 15 patients have been included in this study. 14 patients underwent multislice CT with triphasic acquisition (unenhanced, pancreatic parenchymal and portal venous phases). In 9 cases a delayed phase (120 sec) was also acquired. 5 patients underwent MRI, before and after administration of gadolinium. RESULTS: The mean time interval between nephrectomy and recurrence was 7.5 years (range 1-17 years). On CT metastases avidly enhanced in the parenchymal phase and then demonstrated a significant wash-out, approaching isodensity to the normal pancreatic parenchyma in the portal phase. In the portal phase 20 of the 25 lesions found in the arterial phase were recognizable. On non-enhanced scans, only 13 of the 25 lesions were detected. CONCLUSION: Renal Cell Carcinomas require a prolonged CT or MRI follow-up.