Pick Topic
Review Topic
List Experts
Examine Expert
Save Expert
  Site Guide ··   
Pancreatic Neoplasms: HELP
Articles by Marta Panzeri
Based on 1 article published since 2010
(Why 1 article?)
||||

Between 2010 and 2020, Marta Panzeri wrote the following article about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Article Ct radiomic features of pancreatic neuroendocrine neoplasms (panNEN) are robust against delineation uncertainty. 2019

Mori, Martina / Benedetti, Giulia / Partelli, Stefano / Sini, Carla / Andreasi, Valentina / Broggi, Sara / Barbera, Maurizio / Cattaneo, Giovanni M / Muffatti, Francesca / Panzeri, Marta / Falconi, Massimo / Fiorino, Claudio / De Cobelli, Francesco. ·Medical Physics, San Raffaele Scientific Institute, Milano, Italy. · Radiology, San Raffaele Scientific Institute, Milano, Italy. · Pancreatic Surgery Unit, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milano, Italy; Vita-Salute University, Milano, Italy. · Pancreatic Surgery Unit, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milano, Italy. · Radiology, San Raffaele Scientific Institute, Milano, Italy; Vita-Salute University, Milano, Italy. · Medical Physics, San Raffaele Scientific Institute, Milano, Italy. Electronic address: fiorino.claudio@hsr.it. ·Phys Med · Pubmed #30738530.

ABSTRACT: PURPOSE: The aim of this study was to quantify the impact of CT delineation uncertainty of pancreatic neuroendocrine neoplasms (panNEN) on Radiomic features (RF). METHODS: Thirty-one previously operated patients were considered. Three expert radiologists contoured panNEN lesions on pre-surgical high-resolution contrast-enhanced CT images and contours were transferred onto pre-contrast CT. Volume agreement was quantified by the DICE index. After images resampling and re-binning, 69 RF were extracted and the impact of inter-observer variability was assessed by Intra-Class Correlation (ICC): ICC > 0.80 was considered as a threshold for "very high" inter-observer agreement. RESULTS: The median volume was 1.3 cc (range: 0.2-110 cc); a satisfactory inter-observer volume agreement was found (mean DICE = 0.78). Only 4 RF showed ICC < 0.80 (0.48-0.73), including asphericity and three RFs (of five) of the neighborhood intensity difference matrix (NID). CONCLUSIONS: The impact of inter-observer variability in delineating panNEN on RF was minimum, with the exception of the NID family and asphericity, showing a moderate agreement. These results support the feasibility of studies aiming to assess CT radiomic biomarkers for panNEN.