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Pancreatic Neoplasms: HELP
Articles by Fabio Pacelli
Based on 2 articles published since 2010
(Why 2 articles?)
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Between 2010 and 2020, Fabio Pacelli wrote the following 2 articles about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Clinical Trial Quality of life and toxicity of stereotactic radiotherapy in pancreatic tumors: a case series. 2012

Macchia, Gabriella / Morganti, Alessio G / Cilla, Savino / Ippolito, Edy / Massaccesi, Mariangela / Picardi, Vincenzo / Mattiucci, Gian Carlo / Bonomo, Pierluigi / Tambaro, Rosa / Pacelli, Fabio / Piermattei, Angelo / De Spirito, Marco / Valentini, Vincenzo / Cellini, Numa / Deodato, Francesco. ·Radiotherapy Unit, Fondazione di Ricerca e Cura Giovanni Paolo II, Università-Cattolica, Campobasso, Italy. gmacchia@rm.unicatt.it ·Cancer Invest · Pubmed #22250589.

ABSTRACT: AIM: To analyze the results of extracranial stereotactic radiotherapy (ESRT) experience in pancreatic cancer patients. METHODS: Four noncoplanar fixed beams were used in all patients. RESULTS: Analysis of 16 patients was carried out. Overall response rate was 56.2%. Fifteen patients experienced local and/or distant progression of disease (median follow-up: 24 months). Two-year local progression-free, distant progression-free, and overall survivals were 85.7%, 58.7%, and 50.0%, respectively. Toxicity was less than grade 2 in all, although 1 patient had severe duodenal bleeding. Quality of life scores were unchanged. CONCLUSIONS: ESRT was associated with low complication rate, and not worsening the patients' quality of life.

2 Article Clinical target volume delineation including elective nodal irradiation in preoperative and definitive radiotherapy of pancreatic cancer. 2012

Caravatta, Luciana / Sallustio, Giuseppina / Pacelli, Fabio / Padula, Gilbert D A / Deodato, Francesco / Macchia, Gabriella / Massaccesi, Mariangela / Picardi, Vincenzo / Cilla, Savino / Marinelli, Alfonso / Cellini, Numa / Valentini, Vincenzo / Morganti, Alessio G. ·Radiotherapy Unit, Department of Oncology, Fondazione di Ricerca e Cura Giovanni Paolo II, Università Cattolica del S, Cuore, Largo A, Gemelli 1, 86100, Campobasso, Italy. ·Radiat Oncol · Pubmed #22691275.

ABSTRACT: BACKGROUND: Radiotherapy (RT) is widely used in the treatment of pancreatic cancer. Currently, recommendation has been given for the delineation of the clinical target volume (CTV) in adjuvant RT. Based on recently reviewed pathologic data, the aim of this study is to propose criteria for the CTV definition and delineation including elective nodal irradiation (ENI) in the preoperative and definitive treatment of pancreatic cancer. METHODS: The anatomical structures of interest, as well as the abdominal vasculature were identified on intravenous contrast-enhanced CT scans of two different patients with pancreatic cancer of the head and the body. To delineate the lymph node area, a margin of 10 mm was added to the arteries. RESULTS: We proposed a set of guidelines for elective treatment of high-risk nodal areas and CTV delineation. Reference CT images were provided. CONCLUSIONS: The proposed guidelines could be used for preoperative or definitive RT for carcinoma of the head and body of the pancreas. Further clinical investigations are needed to validate the defined CTVs.