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Pancreatic Neoplasms: HELP
Articles by Giampiero Macarri
Based on 7 articles published since 2008
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Between 2008 and 2019, Giampiero Macarri wrote the following 7 articles about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Editorial [Endoscopic ultrasound in the diagnosis of pancreatic cystic lesions]. 2013

Antonini, Filippo / Macarri, Giampiero. · ·Recenti Prog Med · Pubmed #24336622.

ABSTRACT: Pancreatic cystic lesions are increasingly being detected in clinical practice. They are commonly asymptomatic and incidentally discovered. Distinction between neoplastic and benign lesions is crucial for determining treatment but definite diagnosis is often difficult. Endoscopic ultrasound (EUS), with additional EUS-guided fine needle aspiration (EUS-FNA), has emerged as an ideal technique in the evaluation of these lesions.

2 Review Management of serous cystic neoplasms of the pancreas. 2015

Antonini, Filippo / Fuccio, Lorenzo / Fabbri, Carlo / Macarri, Giampiero / Palazzo, Laurent. ·Department of Gastroenterology, A.Murri Hospital, Polytechnic University of Marche, Fermo, Italy. ·Expert Rev Gastroenterol Hepatol · Pubmed #24981593.

ABSTRACT: Pancreatic serous cystadenomas are uncommon benign tumours that are often found incidentally on routine imaging examinations. Radiological imaging techniques alone have proven to be suboptimal to fully characterize cystic pancreatic lesions. Endoscopic ultrasound, with the addition of fine-needle aspiration in difficult cases, has showed greater diagnostic accuracy than conventional imaging techniques. The best management strategy of these neoplasms is still debated. Surgery should be limited only to symptomatic and highly selected cases and most of the patients should only be strictly monitored. In the current paper, we provide an updated overview on pancreatic serous cystadenomas, focusing our attention on epidemiology, clinical characteristics and diagnostic evaluation; finally, we also discuss different management strategies and areas for future research.

3 Article Biliary plastic stent does not influence the accuracy of endoscopic ultrasound-guided sampling of pancreatic head masses performed with core biopsy needles. 2017

Antonini, Filippo / Fuccio, Lorenzo / Giorgini, Sara / Fabbri, Carlo / Frazzoni, Leonardo / Scarpelli, Marina / Macarri, Giampiero. ·Division of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, Fermo, Italy. Electronic address: filippore@yahoo.it. · Division of Gastroenterology, Department of Medical and Surgical Sciences, S.Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. · Pathological Anatomy and Histopathology, Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy. · Unit of Gastroenterology and Digestive Endoscopy, AUSL Bologna, Bellaria-Maggiore Hospital, Bologna, Italy. · Division of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, Fermo, Italy. ·Dig Liver Dis · Pubmed #28465092.

ABSTRACT: OBJECTIVE: While the presence of biliary stent significantly decreases the accuracy of endoscopic ultrasound (EUS) for pancreatic head cancer staging, its impact on the EUS-guided sampling accuracy is still debated. Furthermore, data on EUS-fine needle biopsy (EUS-FNB) using core biopsy needles in patients with pancreatic mass and biliary stent are lacking. The aim of this study was to evaluate the influence of biliary stent on the adequacy and accuracy of EUS-FNB in patients with pancreatic head mass. METHODS: All patients who underwent EUS-guided sampling with core needles of solid pancreatic head masses causing obstructive jaundice were retrospectively identified in a single tertiary referral center. Adequacy, defined as the rate of cases in which a tissue specimen for proper examination was achieved, with and without biliary stent, was the primary outcome measure. The diagnostic accuracy and complication rate were the secondary outcome measures. RESULTS: A total of 130 patients with pancreatic head mass causing biliary obstruction were included in the study: 74 cases of them were sampled without stent and 56 cases with plastic stent in situ. The adequacy was 96.4% in the stent group and 90.5% in the group without stent (p=0.190). No significant differences were observed for sensitivity (88.9% vs. 85.9%), specificity (100% for both groups), and accuracy (89.3% vs. 86.5%) between those with and without stent, respectively. The accuracy was not influenced by the timing of stenting (<48h or ≥48h before EUS). No EUS-FNB related complications were recorded. CONCLUSION: The presence of biliary stent does not influence the tissue sampling adequacy, the diagnostic accuracy and the complication rate of EUS-FNB of pancreatic head masses performed with core biopsy needles.

4 Article The presence of rapid on-site evaluation did not increase the adequacy and diagnostic accuracy of endoscopic ultrasound-guided tissue acquisition of solid pancreatic lesions with core needle. 2017

Fabbri, Carlo / Fuccio, Lorenzo / Fornelli, Adele / Antonini, Filippo / Liotta, Rosa / Frazzoni, Leonardo / Larghi, Alberto / Maimone, Antonella / Paggi, Silvia / Gusella, Paolo / Barresi, Luca / Polifemo, Anna Maria / Iovine, Elio / Macarri, Giampiero / Cennamo, Vincenzo / Tarantino, Ilaria. ·Unit of Gastroenterology and Digestive Endoscopy, AUSL Bologna, Bellaria-Maggiore Hospital, 40133, Bologna, Italy. carlo.fabbri@ausl.bologna.it. · Division of Gastroenterology, Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy. · Pathology Service, AUSL Bologna, Bellaria-Maggiore Hospital, Bologna, Italy. · Department of Gastroenterology, A. Murri Hospital, Fermo, Italy. · Pathology Service, Department of Diagnostic and Therapeutic Services, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy. · Digestive Endoscopy Unit, Catholic University, Rome, Italy. · Unit of Gastroenterology and Digestive Endoscopy, AUSL Bologna, Bellaria-Maggiore Hospital, 40133, Bologna, Italy. · Gastroenterology Unit, Valduce Hospital, Como, Italy. · Pathology Service, A. Murri Hospital, Polytechnic University of Marche, Fermo, Italy. · Endoscopy Service, Department of Diagnostic and Therapeutic Services, Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT), Palermo, Italy. · Emergency and General Surgery Department, AUSL Bologna, Bellaria-Maggiore Hospital, Bologna, Italy. ·Surg Endosc · Pubmed #27194261.

ABSTRACT: BACKGROUND: Rapid on-site evaluation (ROSE) improves the adequacy and accuracy of EUS-guided tissue acquisition, although it is not routinely widely available. Evidence suggested that core needles might overcome the absence of ROSE. The aim of this study was to evaluate the influence of ROSE on the adequacy and accuracy of EUS-guided tissue acquisition with core needles in patients with pancreatic solid lesions. METHODS: Patients who underwent EUS-guided tissue acquisition of pancreatic mass lesions were retrospectively identified at three tertiary referral centers and those performed with the core needle were included. Adequacy, defined as the rate of cases in which a tissue specimen for proper examination was achieved, with and without ROSE was the primary outcome measure. The diagnostic accuracy and tissue core acquisition were the secondary outcome measures. RESULTS: A total of 333 patients with pancreatic solid mass lesions were included in the study; 140 cases sampled with ROSE and 193 cases without ROSE. The adequacy was 92.1 % in the group sampled with ROSE and 88.1 % in the group without ROSE (p = 0.227). In the ROSE group sensitivity, specificity, and accuracy were 90.7, 100 and 92.1 %, respectively. In the group without ROSE, sensitivity, specificity, and accuracy were 87.2, 100, and 88.1 %, respectively. No difference for all these figures was observed between the two groups. The tissue core was available in 61.4 and 53.4 % of cases with and without ROSE, respectively (p = 0.143). CONCLUSION: In the absence of ROSE, EUS-based tissue acquisition with Core needle should be considered since it achieves comparable tissue sampling adequacy and accuracy.

5 Article Endoscopic ultrasound diagnosis of a primary hepatoid carcinoma of the pancreas. 2015

Antonini, Filippo / Angelelli, Lucia / Rubini, Corrado / Macarri, Giampiero. ·Department of Gastroenterology, A. Murri Hospital, Polytechnic University of Marche, Fermo, Italy. · Medical Oncology, Mazzoni Hospital, Ascoli Piceno, Italy. · Pathological Anatomy and Histopathology, Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy. ·Endoscopy · Pubmed #26262449.

ABSTRACT: -- No abstract --

6 Article Endoscopic ultrasound-guided fine-needle aspiration of an unusual pancreatic mass. 2015

Antonini, Filippo / Santinelli, Alfredo / Macarri, Giampiero. ·Department of Gastroenterology, A. Murri Hospital, Polytechnic University of Marche, Fermo, Italy. · Pathological Anatomy and Histopathology, Department of Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona, Italy. ·Clin Gastroenterol Hepatol · Pubmed #25220936.

ABSTRACT: -- No abstract --

7 Minor Endoscopic ultrasonography in chronic asymptomatic pancreatic hyperenzymemia: Why not? 2018

Antonini, Filippo / Macarri, Giampiero / Pezzilli, Raffaele. ·Department of Gastroenterology, A. Murri Hospital, Polytechnic University of Marche, Fermo, Italy. Electronic address: filippore@yahoo.it. · Department of Gastroenterology, A. Murri Hospital, Polytechnic University of Marche, Fermo, Italy. · Department of Digestive Diseases and Internal Medicine, Sant'Orsola-Malpighi Hospital, Bologna, Italy. ·Dig Liver Dis · Pubmed #28965823.

ABSTRACT: -- No abstract --