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Pancreatic Neoplasms: HELP
Articles by Derek LeRoith
Based on 3 articles published since 2009
(Why 3 articles?)
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Between 2009 and 2019, Derek LeRoith wrote the following 3 articles about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Editorial Foreword: Gastroenteropancreatic system and its tumors: Part 2. 2011

LeRoith, Derek. ·Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA. derek.leroith@mssm.edu ·Endocrinol Metab Clin North Am · Pubmed #21349407.

ABSTRACT: -- No abstract --

2 Editorial Foreword: Gastroenteropancreatic system and its tumors: Part 1. 2010

LeRoith, Derek. ·Division of Endocrinology, Metabolism, and Bone Diseases, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA. derek.leroith@mssm.edu ·Endocrinol Metab Clin North Am · Pubmed #21095537.

ABSTRACT: -- No abstract --

3 Review Type 2 diabetes and cancer: what is the connection? 2010

Cannata, Dara / Fierz, Yvonne / Vijayakumar, Archana / LeRoith, Derek. ·Mount Sinai School of Medicine, New York, NY, USA. ·Mt Sinai J Med · Pubmed #20309918.

ABSTRACT: Epidemiological studies have demonstrated an association between type 2 diabetes and cancer. Type 2 diabetes is characterized by insulin resistance and hyperinsulinemia. Hyperinsulinemia may lead to cancer through insulin's effect on its cognate receptor and the insulin-like growth factor system. The effects of insulin and insulin-like growth factor I on cancer development and progression have been demonstrated in animal and human studies. Type 2 diabetes has been positively associated with cancers of the breast, colon, and pancreas. An inverse relationship has been observed between type 2 diabetes and prostate cancer, and this may be due to lower testosterone levels in men with type 2 diabetes. Medications used to treat type 2 diabetes may affect cancer cells directly or indirectly by affecting serum insulin levels. Hyperinsulinemia may be an important risk factor for cancer as well as a target for cancer therapy.