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Pancreatic Neoplasms: HELP
Articles by Jacopo Desiderio
Based on 5 articles published since 2010
(Why 5 articles?)
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Between 2010 and 2020, Jacopo Desiderio wrote the following 5 articles about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Review Current status of robotic distal pancreatectomy: a systematic review. 2013

Cirocchi, Roberto / Partelli, Stefano / Coratti, Andrea / Desiderio, Jacopo / Parisi, Amilcare / Falconi, Massimo. ·Digestive Surgery and Liver Unit, S. Maria Hospital, Via Tristano di Joannuccio n.4, Terni 05100, Italy. cirocchiroberto@yahoo.it ·Surg Oncol · Pubmed #23910929.

ABSTRACT: OBJECTIVE: The aim of this systematic review is to determine the potential advantages of robotic distal pancreatectomy (RDP). STUDY SELECTION: Both randomized and non-randomized studies. DATA EXTRACTION: Two investigators independently selected studies for inclusion by article abstraction and full text reviewing. DATA SYNTHESIS: Five non-RCTs were included in the review. The feasibility of RDP (95.4%) and spleen-preserving rate is between 50% and 100%. Mean OT varied between 298 min and 398 min with only completely robotic procedures, whereas mean OT was 293 in "laparoscopic/robotic" technique. Postoperative length of hospital stay ranged from 7 days to 13.7 days. The 30-day postoperative overall morbidity resulted between 0 and 18% of patients. CONCLUSIONS: RDP is an emergent technology for which there are not yet sufficient data to draw definitive conclusions with respect to conventional or laparoscopic surgery. The mean duration of RDP is longer with Da Vinci robot, but hospital stay is shorter even if it is influenced by hospital protocols. We cannot make any conclusions comparing the outcomes to laparoscopic or open procedures here, since none of these studies are randomized, and we all know that most of these surgeons selected the easier cases for robotic procedures. For these reasons randomized controlled trials are recommended to better evaluate RDP cost-effectiveness.

2 Article Distal pancreatectomy with splenic preservation: A short-term outcome analysis of the Warshaw technique. 2015

Boselli, Carlo / Barberini, Francesco / Listorti, Chiara / Castellani, Elisa / Renzi, Claudio / Corsi, Alessia / Grassi, Veronica / Cacurri, Alban / Desiderio, Jacopo / Trastulli, Stefano / Santoro, Alberto / Pironi, Daniele / Burattini, Federica / Cirocchi, Roberto / Avenia, Nicola / Noya, Giuseppe / Parisi, Amilcare. ·Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: carloboselli@yahoo.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: francescobarberini@hotmail.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: chiaralist@gmail.com. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: elisa.ecv@gmail.com. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: renzicla@virgilio.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: alessia.cor@libero.it. · Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: veronicagrassi@hotmail.it. · Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: albancacurri@gmail.com. · Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: djdesi85@hotmail.it. · Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: stefano.trastulli@hotmail.it. · Department of Surgical Sciences, Sapienza University of Rome, Italy. Electronic address: albert.santoro@tiscali.it. · Department of Surgical Sciences, Sapienza University of Rome, Italy. Electronic address: danielepironi@gmail.com. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: maria.burattini@unipg.it. · Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: roberto.cirocchi@unipg.it. · Department of General Surgery, Saint Mary Hospital, University of Perugia, Terni, Italy. Electronic address: nicolaavenia@libero.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: giuseppe.noya@unipg.it. · Department of Digestive Surgery, St. Maria Hospital, Terni, Italy. Electronic address: amilcareparisi@virgilio.it. ·Int J Surg · Pubmed #26118603.

ABSTRACT: INTRODUCTION: Spleen-preserving left pancreatectomy (SPDP) with splenic vessels preservation (SVP) or without (Warshaw technique, WT) has been described with robotic, laparoscopy and open surgery. Nevertheless, significant data on medium- and long-term follow-up are still not available, since data in literature are scarce and the level of evidence is low. METHODS: In this retrospective study, we describe and compare short and medium term results of spleen-preserving distal pancreatectomy in eight patients. RESULTS: In WT group the duration and the intraoperative bleeding was superior than SVP group. The incidence of perigastric collateral vessels and presence of submucosal varices evidenced at CT scan was 66% in WT group, while only one case occurred in SVP group. DISCUSSION: The limit of laparoscopic approach is the fact that it needs advanced laparoscopic skills, which might result in intraoperative bleeding and splenectomy. The most of literature considered salvage WT intraoperatively performed in case of classical SVP and not only elective WT. The consequence is that there is no difference in immediate postoperative results (operative time, intraoperative bleeding, hospital stay) that are in favour of SVP because WT is performed only in case of failure in preserving the splenic vessels. In fact when this intervention is performed electively, the procedure time is reduced as well as the intraoperative bleeding. CONCLUSIONS: WT is safe and feasible, even if there are not definitive evidences that demonstrate it is superior to classic SVP. RCTs are needed to determine advantages and disadvantages of WT compared to the classic SVP.

3 Article Can the measurement of amylase in drain after distal pancreatectomy predict post-operative pancreatic fistula? 2015

Cirocchi, Roberto / Graziosi, Luigina / Sanguinetti, Alessandro / Boselli, Carlo / Polistena, Andrea / Renzi, Claudio / Desiderio, Jacopo / Noya, Giuseppe / Parisi, Amilcare / Hirota, Masahiko / Donini, Annibale / Avenia, Nicola. ·Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: roberto.cirocchi@unipg.it. · General and Emergency Surgery, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy. Electronic address: luiginagraziosi@yahoo.it. · Department of General Surgery, Saint Mary Hospital, University of Perugia, Terni, Italy. Electronic address: a.sanguinetti@aospterni.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: carloboselli@yahoo.it. · Department of General Surgery, Saint Mary Hospital, University of Perugia, Terni, Italy. Electronic address: apolis74@yahoo.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: renzicla@virgilio.it. · Department of General and Oncologic Surgery, University of Perugia, Terni, Italy. Electronic address: djdesi85@hotmail.it. · Department of General and Oncologic Surgery, University of Perugia, Perugia, Italy. Electronic address: giuseppe.noya@unipg.it. · Department of Digestive Surgery, St. Maria Hospital, Terni, Italy. Electronic address: amilcareparisi@virgilio.it. · Kumamoto Regional Medical Center, Japan. Electronic address: mhirota@krmc.or.jp. · General and Emergency Surgery, Santa Maria della Misericordia Hospital, University of Perugia, Perugia, Italy. Electronic address: annibale.donini@unipg.it. · Department of General Surgery, Saint Mary Hospital, University of Perugia, Terni, Italy. Electronic address: nicolaavenia@libero.it. ·Int J Surg · Pubmed #26117433.

ABSTRACT: INTRODUCTION: The most frequent reason for performing a distal pancreatectomy is the presence of cystic or neuroendocrine tumors, in which the distal pancreatic stump is often soft and non fibrotic. This parenchymal consistence represents the main risk factor for post-operative pancreatic fistula. In order to identify the fistula and assessing its severity postoperative monitoring of amylase from intraperitoneal drains is important. METHODS: From a retrospective multicentric database analysis were included 33 patients who underwent distal pancreatectomy for pancreatic neoplastic disease. RESULTS: Postoperative pancreatic fistula occurred in four cases. One patient had a ductal adenocarcinoma, two presented with pancreatic endocrine neoplasms and the last one had an intraductal papillary mucinous neoplasia. Two patients underwent open, the other two laparoscopic distal pancreatectomy. DISCUSSION: Postoperative pancreatic fistulas after distal pancreatectomy worsen the quality of life, prolong the post-operative stay and delay further adjuvant therapy. In patients who underwent distal pancreatectomy literature exposed some advantages deriving from the placement of abdominal drainages only in selected cases and from their early removal. Patients presenting a high risk of pancreatic fistula had higher amylase levels of drainage fluid in the first postoperative day. CONCLUSION: POPF is the most frequently complication after pancreatectomy. In our analysis DFA1>5000 can be considered as a predictive factor for pancreatic fistula. For this reason, the systematic measurement of amylase in drain fluid in first-postoperative day can be considered a good clinical practice.

4 Article Road accident due to a pancreatic insulinoma: a case report. 2015

Parisi, Amilcare / Desiderio, Jacopo / Cirocchi, Roberto / Grassi, Veronica / Trastulli, Stefano / Barberini, Francesco / Corsi, Alessia / Cacurri, Alban / Renzi, Claudio / Anastasio, Fabio / Battista, Francesca / Pucci, Giacomo / Noya, Giuseppe / Schillaci, Giuseppe. ·From the Unit of Digestive and Liver Surgery (AP, JD, VG, ST, AC), Santa Maria Hospital, Terni · Department of General and Oncologic Surgery (RC, FB, AC, CR, GN), University of Perugia, Perugia · Unit of Internal Medicine (FA, FB, GP, GS), Santa Maria Hospital, Terni · and Department of Medicine (FA, FB, GP, GS), University of Perugia, Perugia, Italy. ·Medicine (Baltimore) · Pubmed #25816027.

ABSTRACT: Insulinoma is a rare pancreatic endocrine tumor, typically sporadic and solitary. Although the Whipple triad, consisting of hypoglycemia, neuroglycopenic symptoms, and symptoms relief with glucose administration, is often present, the diagnosis may be challenging when symptoms are less typical. We report a case of road accident due to an episode of loss of consciousness in a patient with pancreatic insulinoma. In the previous months, the patient had occasionally reported nonspecific symptoms. During hospitalization, endocrine examinations were compatible with an insulin-producing tumor. Abdominal computerized tomography and magnetic resonance imaging allowed us to identify and localize the tumor. The patient underwent a robotic distal pancreatectomy with partial omentectomy and splenectomy. Insulin-producing tumors may go undetected for a long period due to nonspecific clinical symptoms, and may cause episodes of loss of consciousness with potentially lethal consequences. Robot-assisted procedures can be performed with the same techniques of the traditional surgery, reducing surgical trauma, intraoperative blood loss, and hospital stays.

5 Article Robotic distal pancreatectomy with or without preservation of spleen: a technical note. 2014

Parisi, Amilcare / Coratti, Francesco / Cirocchi, Roberto / Grassi, Veronica / Desiderio, Jacopo / Farinacci, Federico / Ricci, Francesco / Adamenko, Olga / Economou, Anastasia Iliana / Cacurri, Alban / Trastulli, Stefano / Renzi, Claudio / Castellani, Elisa / Di Rocco, Giorgio / Redler, Adriano / Santoro, Alberto / Coratti, Andrea. ·Department of Digestive and Liver Surgery Unit, St Maria Hospital, Viale Tristano di Joannuccio 1, 05100 Terni, Italy. veronicagrassi@hotmail.it. ·World J Surg Oncol · Pubmed #25248464.

ABSTRACT: BACKGROUND: Distal pancreatectomy (DP) is a surgical procedure performed to remove the pancreatic tail jointly with a variable part of the pancreatic body and including a spleen resection in the case of conventional distal pancreatectomy or not in the spleen-preserving distal pancreatectomy. METHODS: In this article, we describe a standardized operative technique for fully robotic distal pancreatectomy. RESULTS: In the last decade, the use of robotic systems has become increasingly common as an approach for benign and malignant pancreatic disease treatment. Robotic Distal Pancreatectomy (RDP) is an emerging technology for which sufficient data to draw definitive conclusions in surgical oncology are still not available because the follow-up period after surgery is too short (less than 2 years). CONCLUSIONS: RDP is an emerging technology for which sufficient data to draw definitive conclusions of value in surgical oncology are still not available, however this techniques is safe and reproducible by surgeons that possess adequate skills.