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Pancreatic Neoplasms: HELP
Articles by Benedetta Pontillo Contillo
Based on 1 article published since 2010
(Why 1 article?)

Between 2010 and 2020, Benedetta Pontillo Contillo wrote the following article about Pancreatic Neoplasms.
+ Citations + Abstracts
1 Article Contrast enhancement pattern on multidetector CT predicts malignancy in pancreatic endocrine tumours. 2015

Cappelli, Carla / Boggi, Ugo / Mazzeo, Salvatore / Cervelli, Rosa / Campani, Daniela / Funel, Niccola / Contillo, Benedetta Pontillo / Bartolozzi, Carlo. ·Diagnostic and Interventional Radiology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, carlacappelli1@gmail.com. ·Eur Radiol · Pubmed #25447971.

ABSTRACT: OBJECTIVES: Preoperative suspicion of malignancy in pancreatic neuroendocrine tumours (pNETs) is mostly based on tumour size. We retrospectively reviewed the contrast enhancement pattern (CEP) of a series of pNETs on multiphasic multidetector computed tomography (MDCT), to identify further imaging features predictive of lesion aggressiveness. METHODS: Sixty pNETs, diagnosed in 52 patients, were classified based on CEP as: type A showing early contrast enhancement and rapid wash-out; type B presenting even (B1) or only (B2) late enhancement. All tumours were resected allowing pathologic correlations. RESULTS: Nineteen pNETs showed type A CEP (5-20 mm), 29 type B1 CEP (5-80 mm) and 12 type B2 (15-100 mm). All tumours were classified as well differentiated tumours, 19 were benign (WDt-b), 15 with uncertain behaviour (WDt-u) and 26 carcinomas (WDC). None of A lesions were malignant (12 WDt-b; 7 WDt-u), all B2 lesions were WDC, 7 B1 lesions were WDt-b, 8 WDt-u and 14 WDC; 4/34 (12 %) lesions ≤2cm were WDC. CEP showed correlation with all histological prognostic indicators. CONCLUSIONS: Correlating with the lesion grading and other histological prognostic predictors, CEP may preoperatively suggest the behaviour of pNETs, assisting decisions about treatment. Moreover CEP allows recognition of malignant small tumours, incorrectly classified on the basis of their dimension.