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Pancreatic Neoplasms: HELP
Articles by Therese Becker
Based on 1 article published since 2008
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Between 2008 and 2019, Therese Becker wrote the following article about Pancreatic Neoplasms.
 
+ Citations + Abstracts
1 Review Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research. 2017

Pang, Tony C Y / Xu, Zhihong / Pothula, Srinivasa / Becker, Therese / Goldstein, David / Pirola, Romano C / Wilson, Jeremy S / Apte, Minoti V. ·Pancreatic Research Group, South Western Sydney Clinical School,University of New South Wales, and Ingham Institute of Applied Medical Research, Australia and. · Centre for Circulating Tumour Cell Diagnostics and Research, InghamInstitute for Applied Medical Research, South Western Sydney Clinical School, University of New South Wales, and School ofMedicine, Western Sydney University, Australia. ·Carcinogenesis · Pubmed #28379317.

ABSTRACT: Pancreatic stellate cells (PSCs) are known to play an important role in facilitating pancreatic cancer progression-both in terms of local tumour growth as well as the establishment of metastases. We have previously demonstrated that PSCs from the primary cancer seed to distant metastatic sites. We therefore hypothesise that PSCs circulate along with pancreatic cancer cells (circulating tumour cells-CTCs) to help create a growth permissive microenvironment at distant metastatic sites. This review aims to explore the concept of circulating PSCs in pancreatic cancer and suggests future directions for research in this area.