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Hearing Disorders: HELP
Articles by Terje A. Osnes
Based on 2 articles published since 2010
(Why 2 articles?)

Between 2010 and 2020, Terje Osnes wrote the following 2 articles about Hearing Disorders.
+ Citations + Abstracts
1 Article Long-term ototoxicity in women after cisplatin treatment for ovarian germ cell cancer. 2017

Skalleberg, Jakob / Solheim, Olesya / Fosså, Sophie D / Småstuen, Milada Cvancarova / Osnes, Terje / Gundersen, Per Ole M / Bunne, Marie. ·Department of Otolaryngology, Head and Neck Surgery, Rikshospitalet, Oslo University Hospital, Norway. · Department of Gynecological Oncology, Radiumhospitalet, Oslo University Hospital, Norway. · National Resource Center for Late Effects after Cancer Treatment, Radiumhospitalet, Oslo University Hospital, Norway. Electronic address: sopfos@ous-hf.no. · Department of Health Science and Biostatistics, Høgskolen i Oslo og Akershus, Norway. · Department of Clinical Pharmacology, St Olav University Hospital, Trondheim, Norway. ·Gynecol Oncol · Pubmed #28202195.

ABSTRACT: OBJECTIVE: Evaluate long-term cisplatin-induced ototoxicity in women treated for malignant ovarian germ cell tumors (MOGCT). METHODS: Seventy-four women treated for MOGCT in Norway (1980-2009) were analyzed: 41 had received cisplatin-based chemotherapy (CBCT) ("Cases") and 33 had no CBCT ("Controls"). Median follow-up was 15years. Hearing was assessed by pure tone audiometry and by the SCIN questionnaire. Air conduction thresholds were reported as absolute hearing thresholds and age-adjusted thresholds. Absolute and age-adjusted hearing loss were defined as thresholds of >20dB at any frequency. Tinnitus was evaluated using the Tinnitus Handicap Inventory. Serum Platinum Concentration (SPC) was determined. RESULTS: Absolute hearing loss was identified in 21 Cases (51%) and 24 Controls (73%). After adjusting for age, only 9 Cases (22%) and 5 Controls (15%) remained. Age-adjusted hearing thresholds at 4, 6 and 8kHz were slightly but significantly higher in Cases compared to Controls. Subjective hearing loss was reported by 27% of Cases and 21% of Controls, who were significantly older. Elevated SPC values were detected up to 20years after CBCT, but SPC did not correlate significantly with age-adjusted hearing loss. The rate of tinnitus was similar in Cases and Controls. CONCLUSION: Long-term MOGCT survivors treated with CBCT have small but significant reductions in age-adjusted hearing thresholds at 4, 6 and 8kHz versus Controls. Approximately one in four women experienced subjective hearing loss. To avoid overestimation of clinically relevant cisplatin-induced ototoxicity, absolute hearing thresholds should be age-adjusted and compared to an age-matched control group.

2 Article Sound localising ability in children with bilateral sequential cochlear implants. 2012

Strøm-Roum, Henrik / Rødvik, Arne K / Osnes, Terje A / Fagerland, Morten W / Wie, Ona B. ·University of Oslo, Norway. henrik.strom-roum@oslo-universitetssykehus.no ·Int J Pediatr Otorhinolaryngol · Pubmed #22721525.

ABSTRACT: OBJECTIVES: To evaluate the sound localisation ability in children with sequential bilateral cochlear implants and the potential influence of age at the time of the first implantation, years of experience with the first implanted ear and the inter-implant interval (time between the first and the second cochlear implantation). METHODS: Sixty-three prelingually deaf children (mean age, 11.03; range, 6.5-17 years; SD, 3.09) were tested after 12 and 24 months of using bilateral cochlear implants. Every child was tested with each ear alone and both ears together. Five loudspeakers were placed in a 180° horizontal arch with 45° of separation between each loudspeaker. The child was placed 1.5m from the speakers. For each test run, three stimuli were presented at 65dB (A) from each speaker for a total of 15 stimulus presentations. For each test run, we calculated the mean angular error (MAE) and the proportion of correct speakers identified (CSS: correct speaker score). Performance by chance for the MAE was 72° and for the CSS was 20% (1 of 5 speakers). RESULTS: After 12 months of using bilateral CIs, the added effect of the second CI in the MAE was minor, and there was no significant difference in CSS between listening in the unilateral condition and listening in bilateral condition. After 24 months, however, the added effect of the second CI in the MAE was significant (mean diff=12.2°; 95% CI; 4.5-20.0°, p=0.003). The mean bilateral CSS increased significantly to 38% (diff=7.7%; 95% CI; 1.4-14.0%; p=0.019) while the mean unilateral CSS remained at a similar level (27%). The influence of age at the time of the first implantation on CSS after 24 months was not significant (p=0.96). However, the inter-implant interval showed a significant decrease in score by 1.4% per year between the two implants (p=0.04). CONCLUSION: Sound localisation with two versus one CI in children with a sequential bilateral cochlear implantation was significantly improved 24 months (but not 12 months) after the second implantation. A shorter inter-implant interval showed a small but significant beneficial effect on sound localisation.