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Hearing Disorders: HELP
Articles by Alessandra Murri
Based on 9 articles published since 2010
(Why 9 articles?)
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Between 2010 and 2020, A. Murri wrote the following 9 articles about Hearing Disorders.
 
+ Citations + Abstracts
1 Clinical Trial Narrative abilities in early implanted children. 2015

Murri, Alessandra / Cuda, Domenico / Guerzoni, Letizia / Fabrizi, Enrico. ·Department of Otorhinolaryngology, Guglielmo da Saliceto Hospital (a.m., d.c., l.g.), Piacenza, Italy. · Department of Economics and Social Sciences, Università Cattolica del S. Cuore Piacenza (e.f.), Piacenza, Italy. ·Laryngoscope · Pubmed #25510218.

ABSTRACT: OBJECTIVES/HYPOTHESIS: To investigate the effect of age at cochlear implant activation on oral narrative ability in children implanted before 2.5 years of age and to examine the role of other variables (gender, parental education level, stimulation modality) in narrative skills. STUDY DESIGN: retrospective nonrandomized group study METHODS: Thirty children (21 females; 9 males) with congenital, bilateral severe-to-profound sensorineural hearing loss were included in this study. The mean age at cochlear implant activation was 14.7 months (standard deviation [SD] ± 5.3). The Renfrew Bus Story was used to analyze oral narrative skills at mean chronological age of 63 months (SD ± 0.2). RESULTS: The total information on the Renfrew Bus Story raw score ranged from 8 to 40, with a mean of 22.7 (SD ± 8.6). Children produced on average 7.5 words in a sentence (SD ± 1.5). The mean score for complexity was 2.2 (SD ± 1.5). Regression analysis revealed a highly significant and negative linear effect of age at cochlear implant activation on all outcomes. The mother's education level had a positive strong effect on sentence length but a weak effect on total information and complexity. The paternal education score had a weak influence on the sentence length. Gender, age at diagnosis, and stimulation modality were not correlated with the narrative outcomes. CONCLUSIONS: Early implanted children can develop narrative skills close to normal hearing children. The sociocultural context, expressed by maternal and paternal educational level, are positively related to the development of oral narrative.

2 Article Early prelingual auditory development in Italian infants and toddlers analysed through the Italian version of the Infant-Toddler Meaningful Auditory Integration Scale (IT-MAIS). 2018

Cavicchiolo, S / Mozzanica, F / Guerzoni, L / Murri, A / Dall'Ora, I / Ambrogi, F / Barozzi, S / Cuda, D / Schindler, A. ·Audiology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. · Phoniatric Unit, Department of Biomedical and Clinical Sciences "L. Sacco" Hospital, University of Milan, Via G.B. Grassi 74, 20100, Milan, Italy. francesco.mozzanica@gmail.com. · Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, Piacenza, Italy. · Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy. · Phoniatric Unit, Department of Biomedical and Clinical Sciences "L. Sacco" Hospital, University of Milan, Via G.B. Grassi 74, 20100, Milan, Italy. ·Eur Arch Otorhinolaryngol · Pubmed #29248951.

ABSTRACT: PURPOSE: To evaluate the reliability and validity of the Italian version of the Infant-Toddler Meaningful Auditory Integration Scale (I-IT-MAIS), and to assess the normal trajectory of early prelingual auditory (EPLAD) development from birth to 24 months in a group of normal-hearing Italian children using the I-IT-MAIS. METHODS: The study consisted of four phases: item generation, reliability analysis, assessment of the normal trajectory for EPLAD, and validity analysis. A group of 120 normal-hearing children and a group of 31 deaf children wearing hearing aids and on a waiting list for cochlear implantation were enrolled. All the parents completed the I-IT-MAIS. Sixty of them completed the I-IT-MAIS twice, 2 weeks apart, for test-retest reliability analysis. The I-IT-MAIS scores were used to assess the normal trajectory of EPLAD development from birth to 24 months in normal-hearing children. For criterion validity analysis, the I-IT-MAIS scores were correlated with production of infant scale evaluation (PRISE) scores in 60 normal-hearing children. For discriminant validity analysis, the I-IT-MAIS scores obtained in normal and deaf children were compared. RESULTS: Internal consistency of I-IT-MAIS was satisfactory as well as individual item reliability, test-retest reliability, and discriminant validity. EPLAD development in normal-hearing Italian-speaking children was evaluated. As far as the criterion validity of the I-IT-MAIS is concerned, a strong correlation between I-IT-MAIS and PRISE scores was found. CONCLUSION: I-IT-MAIS is reliable and valid. Its application is recommended for clinical practice and outcome research.

3 Article Cochlear implantation with the nucleus slim modiolar electrode (CI532): a preliminary experience. 2017

Cuda, Domenico / Murri, Alessandra. ·Department of Otorhinolaryngology, 'Guglielmo da Saliceto' Hospital, Via Cantone del Cristo 40, 29121, Piacenza, Italy. · Department of Otorhinolaryngology, 'Guglielmo da Saliceto' Hospital, Via Cantone del Cristo 40, 29121, Piacenza, Italy. alessandra_murri@libero.it. ·Eur Arch Otorhinolaryngol · Pubmed #29032420.

ABSTRACT: To combine the benefits of perimodiolar stimulation with minimal insertion trauma, a thin, pre-curved electrode (CI532) was recently developed by Cochlear Ltd. (Sidney). This array is held straight prior to insertion by an external polymer reloadable sheath that is removed after full electrode insertion. Sixty-seven patients suffering from severe-to-profound sensorineural hearing loss (mean age 42.2 years; mean duration of the hearing loss 19.6 years; mean PTA thresholds at 250-2000 Hz 92.4 dB HL) were implanted with the CI532. Mean duration of surgery was 58.7 min. In 61 patients, a round window (RW) approach was used. In the remaining six cases, a cochleostomy was done because of RW ossification. Impedances and NRT for each electrode are reported. NRT ratio average value was 0.86 ± 0.12 predicting correct scala tympani electrode placement. Post-operative PTA threshold in the implanted ear was 102.9 dB HL. Finally, speech recognition level in quiet at 65 dB HL was 44.6%, after a short follow-up (mean 5.2 months). Our preliminary experience with the new CI532 shows good surgical, electrophysiological, and audiological outcomes. In particular, our results are promising regarding the possibility to achieve minimal insertion trauma and good residual hearing preservation with the use of a deep inserted close modiolar electrode.

4 Article Level of emotion comprehension in children with mid to long term cochlear implant use: How basic and more complex emotion recognition relates to language and age at implantation. 2016

Mancini, Patrizia / Giallini, Ilaria / Prosperini, Luca / D'alessandro, Hilal Dincer / Guerzoni, Letizia / Murri, Alessandra / Cuda, Domenico / Ruoppolo, Giovanni / De Vincentiis, Marco / Nicastri, Maria. ·Department of Sense Organs, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: p.mancini@uniroma1.it. · Department of Sense Organs, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: ilariagiallini@hotmail.com. · Department of Neurology and Psychiatry, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: luca.prosperini@uniroma1.it. · Department of Sense Organs, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: dincer.hilal@gmail.com. · Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, 29121 Piacenza, Italy. Electronic address: guerzoni1@libero.it. · Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, 29121 Piacenza, Italy. Electronic address: alessandra_murri@libero.it. · Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, 29121 Piacenza, Italy. Electronic address: d.cuda@ausl.pc.it. · Department of Sense Organs, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: giovanni.ruoppolo@uniroma1.it. · Department of Sense Organs, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: marco.devincentiis@uniroma1.it. · Department of Sense Organs, University Sapienza of Rome, 00161 Rome, Italy. Electronic address: maria.nicastri@libero.it. ·Int J Pediatr Otorhinolaryngol · Pubmed #27368475.

ABSTRACT: OBJECTIVES: The current study was designed with three main aims: To document the level of emotional comprehension skills, from basic to more complex ones, reached by a wide sample of cochlear implant (CI) deaf children with at least 36 months of device use; To investigate subjective and audiological factors that can affect their emotional development; To identify, if present, a "critical age", in which early intervention might positively affect adequate emotional competence development. DESIGN: This is an observational cohort study. Children with congenital severe/profound deafness were selected based on: aged by 4-11 years, minimum of 36 months of CI use, Italian as the primary language in the family; normal cognitive level and absence of associated disorders or socio-economic difficulties. Audiological characteristics and language development were assessed throughout standardized tests, to measure speech perception in quiet, lexical comprehension and production. The development of emotions' understanding was assessed using the Test of Emotion Comprehension (TEC) of Pons and Harris, a hierarchical developmental model, where emotion comprehension is organized in 3 Stages (external, mental and reflective). Statistical analysis was accomplished via the Spearman Rank Correlation Coefficient, to study the relationship between the personal and audiological characteristics; a multivariate linear regression analysis was carried out to find which variables were better associated with the standardized TEC values; a chi-squared test with Yate's continuity correction and Mann-Whitney U test were used to account for differences between continuous variables and proportions. RESULTS: 72 children (40 females, 32 males) with a mean age of 8.1 years were included. At TEC score, 57 children showed normal range performances (79.17% of recipients) and 15 fell below average (20.83% of recipients). The 16.63% of older subjects (range of age 8-12 years) didn't master the Stage 3 (reflective), which is normally acquired by 8 years of age and failed 2 or all the 3 items of this component. Subjects implanted within 18 months of age had better emotion comprehension skills. TEC results were also positively correlated with an early diagnosis, a longer implant use, better auditory skills and higher scores on lexical and morphosintactic tests. On the contrary, it was negatively correlated with the presence of siblings and the order of birth. The gender, the side and the severity of deafness, type of implant and strategy were not correlated. CONCLUSIONS: Early implanted children have more chance to develop adequate emotion comprehension, especially when the complex aspects are included, due to the very strong link between listening and language skills and emotional development. Furthermore, longer CI auditory experience along with early intervention allows an adequate communication development which positively influences the acquisition of such competencies.

5 Article Cochlear implantation in delayed sudden hearing loss after conservative vestibular schwannoma surgery. 2016

Dagna, F / Murri, A / Albera, R / Cuda, D. ·Department of Surgical Sciences, University of Torino, Italy. · Department of Otorhinolaryngology "Guglielmo da Saliceto" Hospital, Piacenza, Italy. ·Acta Otorhinolaryngol Ital · Pubmed #27070537.

ABSTRACT: This is a case of successful cochlear implantation in a 50-year-old man who experienced sudden hearing loss and developed ipsilateral severe tinnitus at three years following conservative stage 1 vestibular schwannoma retrosigmoid surgery. After cochlear implantation, tinnitus improved from THI grade 4 to 2. Localisation skills improved. Hearing in noise (S/N + 7 dB) with target signal from the operated side improved from 38 to 100% of correct answers. A significant improvement of spatial and speech items of the "speech, spatial and qualities of sounds" questionnaire was also measured. In conclusion, cochlear implantation is a feasible and effective solution after conservative vestibular schwannoma surgery should delayed hearing loss occur.

6 Article The Carina© middle ear implant: surgical and functional outcomes. 2016

Bruschini, Luca / Berrettini, Stefano / Forli, Francesca / Murri, Alessandra / Cuda, Domenico. ·ENT Audiology and Phoniatric Unit, University Hospital of Pisa, Pisa, Italy. l.bruschini@gmail.com. · ENT Audiology and Phoniatric Unit, University Hospital of Pisa, Pisa, Italy. · Division of ENT Diseases, Karolinska Institute, Stockholm, Sweden. · ENT Unit, "Guglielmo da Saliceto" Hospital of Piacenza, Piacenza, Italy. ·Eur Arch Otorhinolaryngol · Pubmed #27007286.

ABSTRACT: The Carina© system (Cochlear Ltd, Sydney, Australia) is a totally implantable prosthesis designed to meet the needs of acoustic amplification in adults with moderate-to-severe sensorineural or mixed hearing loss. It mechanically stimulates the ossicles or labyrinthine windows. The object of this study was to update surgical and functional results obtained in a consistent sample of Carina© recipients. The data sheets of 26 patients who underwent Carina© surgery at two ENT units [i.e., ENT Audiology and Phoniatrics Unit of the University Hospital of Pisa (Pisa, Italy) and ENT Unit of "Guglielmo da Saliceto" Hospital of Piacenza (Piacenza, Italy)] were evaluated for the surgical and audiological outcomes. Twenty patients received a unilateral device, whereas six patients were bilaterally implanted (simultaneously in one patient and sequentially in the remaining five patients). The total number of ears implanted in this study was 32. Most implanted patients expressed a high degree of satisfaction with the prosthesis, which highlights the improvement in hearing in different environmental conditions, the cosmetic advantages, and greater freedom in performing common activities in daily living. Audiological examination demonstrated valid functional gain and significant improvement in speech perception in quiet. Based on this experience, the Carina© is a valid alternative to hearing aids. Moreover, a bilateral implantation, even a simultaneous implantation, is a viable option for selected motivated patients because the intervention is generally well tolerated and the surgery time is relatively fast.

7 Article Social conversational skills development in early implanted children. 2016

Guerzoni, Letizia / Murri, Alessandra / Fabrizi, Enrico / Nicastri, Maria / Mancini, Patrizia / Cuda, Domenico. ·Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, Piacenza, Italy. · Department of Economics and Social Sciences, Università Cattolica del S. Cuore, Piacenza, Italy. · Department of Sense Organs, Sapienza University of Rome, Rome, Italy. ·Laryngoscope · Pubmed #26649815.

ABSTRACT: OBJECTIVES/HYPOTHESIS: Social conversational skills are a salient aspect of early pragmatic development in young children. These skills include two different abilities, assertiveness and responsiveness. This study investigated the development of these abilities in early implanted children and their relationships with lexical development and some language-sensitive variables. STUDY DESIGN: Prospective, observational, nonrandomized study. METHODS: Participants included 28 children with congenital profound sensorineural hearing loss. The mean age at device activation was 13.3 months (standard deviation [SD] ±4.2). The Social-Conversational Skills Rating Scale was used to evaluate assertiveness and responsiveness. The MacArthur-Bates Communicative Development Inventory (Words and Sentences form) was used to analyze the lexical development. The device experience was 12 months for each child, and the mean age at testing was 25.9 months (SD ±4.6). RESULTS: Assertiveness and responsiveness scores were within the normal range of normal-hearing age-matched peers. Age at cochlear implant activation exerted a significant impact, with the highest scores associated to the youngest patients. The residual correlations between assertiveness and responsiveness with the lexical development were positive and strongly significant (r = 0.69 and 0.73, respectively). Preoperative hearing threshold demonstrated an associated significant coefficient on the assertiveness score. Age at diagnosis and maternal education level were not correlated with the social conversational skills. CONCLUSIONS: Early-implanted children developed social conversational skills that are similar to normal-hearing peers matched for age 1 year after device activation. Social conversational skills and lexical development were strongly correlated, but the present study design cannot specify the direction of this relationship. Children with better preoperative residual hearing exhibited better assertive ability. LEVEL OF EVIDENCE: 4 Laryngoscope, 126:2098-2105, 2016.

8 Article Pre-school children have better spoken language when early implanted. 2014

Cuda, Domenico / Murri, Alessandra / Guerzoni, Letizia / Fabrizi, Enrico / Mariani, Valeria. ·Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, Via Cantone del Cristo 40, Piacenza 29121, Italy. Electronic address: domcuda@libero.it. · Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, Via Cantone del Cristo 40, Piacenza 29121, Italy. · Department of Economics and Social Sciences, Università Cattolica del S. Cuore, Via Emilia Parmense 84, Piacenza 29122, Italy. ·Int J Pediatr Otorhinolaryngol · Pubmed #24916102.

ABSTRACT: OBJECTIVES: The objectives of this study were: (1) to investigate the effect of age at cochlear implantation (CI) on vocabulary development; (2) to evaluate the age effect at CI surgery on the syntactic development; and (3) to examine the role of gender, age at first diagnosis and maternal education level on spoken language development. MATERIAL AND METHODS: Retrospective study. Thirty children with congenital severe- to -profound sensorineural hearing loss (SNHL) were sampled. They were diagnosed and fitted with hearing aids through six months of age. They were implanted between 8 and 17 months of age. The MacArthur-Bates Communicative Development Inventory (MCDI) was administrated at the age of 36 months. The total productive vocabulary (word number raw score), the mean length of utterance (M3L) and the sentences complexity were analysed. RESULTS: The average word number raw score was 566.3 for the children implanted before 12 months of age versus 355 for those implanted later. The M3L was 8.3 for those implanted under 1 year versus 4.2 of those implanted later. The average sentences complexity was 82.3% for those receiving CI before 12 months, while it was 24.4% for those underwent at CI after 12 months. Regression analysis revealed a highly significant and negative linear effect of age at CI surgery on all outcomes. Females had better outcomes. Age at diagnosis was not correlated with the linguistic results. The mother's education level had a positive significant effect on sentences complexity. CONCLUSION: The CI in pre-school children with SNHL implanted under 1 year has a positive effect on spoken language. Females seem to have better linguistic results. Finally high maternal educational level appears to have some positive effect on language development.

9 Article Production of infant scale evaluation (PRISE) in Italian normal hearing children: a validation study. 2013

Cuda, Domenico / Guerzoni, Letizia / Mariani, Valeria / Murri, Alessandra / Biasucci, Giacomo / Fabrizi, Enrico. ·Department of Otorhinolaryngology, "Guglielmo da Saliceto" Hospital, Via Cantone del Cristo 40, 29121 Piacenza, Italy. Electronic address: domcuda@libero.it. ·Int J Pediatr Otorhinolaryngol · Pubmed #24148864.

ABSTRACT: OBJECTIVES: Parental questionnaires are important tools in the evaluation of auditory and language skills of very young children affected by sensorineural hearing loss. One of these instruments is the Production on Infant Scale Evaluation (PRISE). The purposes of this study were to adapt and validate the PRISE on Italian children with normal hearing; and to obtain normative data. METHODS: A back translation technique was used to adapt the Italian version of PRISE. The PRISE was submitted to parents of 234 normal children aged between 3 and 18 months of life. All of them passed local universal newborn hearing screenings and they presented no audiological risk factors. RESULTS: The PRISE internal reliability (Cronbach's alpha) was 0.87. Split-half reliability indexes were λ(4) = 0.89 and λ(6) = 0.89. Corrected item-total correlation coefficients were significant for all items. The correlation of PRISE with a modified Infant Toddler Meaningful Auditory Integration Scale (IT-MAIS), collected for convergent validity measurement purposes, was good (r = 0.743). A positive correlation of PRISE scores with age was found, reflecting on the age-dependence of pre-verbal skills. CONCLUSION: These findings demonstrate high reliability and convergent validity of the Italian PRISE version. This questionnaire constitutes a robust tool for assessing early language development in infants and toddlers with normal hearing. It seems particularly sensitive to the normal language development in the first years of life, which can be very useful for early rehabilitation of hearing loss.