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Hearing Disorders: HELP
Articles by Roberta Anzivino
Based on 5 articles published since 2010
(Why 5 articles?)

Between 2010 and 2020, R. Anzivino wrote the following 5 articles about Hearing Disorders.
+ Citations + Abstracts
1 Article Hearing loss in very preterm infants: should we wait or treat? 2019

Frezza, S / Catenazzi, P / Gallus, R / Gallini, F / Fioretti, M / Anzivino, R / Corsello, M / Cota, F / Vento, G / Conti, G. ·Department of Woman and Child Health, Division of Neonatology, Institute of Otorhinolaryngology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy. · Department Head and Neck Surgery, Institute of Otorhinolaryngology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCSS, Rome, Italy. ·Acta Otorhinolaryngol Ital · Pubmed #31501617.

ABSTRACT: -- No abstract --

2 Article Acquired sensorineural hearing loss in children: current research and therapeutic perspectives. 2017

Ralli, M / Rolesi, R / Anzivino, R / Turchetta, R / Fetoni, A R. ·Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy. · Department of Otolaryngology, Catholic University of Sacred Heart, Rome, Italy. · Department of Sense Organs, Sapienza University of Rome, Italy. ·Acta Otorhinolaryngol Ital · Pubmed #29327735.

ABSTRACT: The knowledge of mechanisms responsible for acquired sensorineural hearing loss in children, such as viral and bacterial infections, noise exposure, aminoglycoside and cisplatin ototoxicity, is increasing and progressively changing the clinical management of affected patients. Viral infections are by far the most relevant cause of acquired hearing loss, followed by aminoglycoside and platinum derivative ototoxicity; moreover, cochlear damage induced by noise overexposure, mainly in adolescents, is an emerging topic. Pharmacological approaches are still challenging to develop a truly effective cochlear protection; however, the use of steroids, antioxidants, antiviral drugs and other small molecules is encouraging for clinical practice. Most of evidence on the effectiveness of antioxidants is still limited to experimental models, while the use of corticosteroids and antiviral drugs has a wide correspondence in literature but with controversial safety. Future therapeutic perspectives include innovative strategies to transport drugs into the cochlea, such as molecules incorporated in nanoparticles that can be delivered to a specific target. Innovative approaches also include the gene therapy designed to compensate for abnormal genes or to make proteins by introducing genetic material into cells; finally, regenerative medicine (including stem cell approaches) may play a central role in the upcoming years in hearing preservation and restoration even if its role in the inner ear is still debated.

3 Article Audiologic Assessment in Adults With Down Syndrome. 2017

Picciotti, Pasqualina M / Carfì, Angelo / Anzivino, Roberta / Paludetti, Gaetano / Conti, Guido / Brandi, Vincenzo / Bernabei, Roberto / Onder, Graziano. ·Pasqualina M. Picciotti, Angelo Carfì, Roberta Anzivino, Gaetano Paludetti, Guido Conti, Vincenzo Brandi, Roberto Bernabei, and Graziano Onder, Department of Gerontology, Neurosciences, Head and Neck and Orthopedics, Catholic University of the Sacred Heart, Rome, Italy. ·Am J Intellect Dev Disabil · Pubmed #28654410.

ABSTRACT: Increased life expectancy in persons with Down syndrome (DS) is associated with premature age-related changes. The aim of this study was to assess auditory function in adults with DS and to evaluate the prevalence of hearing loss in this population. Audiometric tests were performed in 72 adults with DS (mean age 37.3±10.1 years, 51.4% females). Air conduction pure tone average (PTA) thresholds at frequencies 0.5-1-2-4 kHz were calculated to assess hearing function. Hearing loss was present if the PTA threshold was > 20 dB hearing level. Higher frequencies of 4 and 8 kHz were also assessed. Hearing loss was shown in 47 (65.3%) participants. The prevalence of hearing loss increased with age, ranging from 42.86% in the 20-29 years group to 90.91% in the 50-59 years group. High frequencies (4 and 8 kHz) were more often impaired than other frequencies used to measure PTA. Thus, the study concluded hearing loss is common in adults with DS and shows a pattern compatible with precocious aging of the hearing system. Auditory evaluation is strongly recommended in adults with DS.

4 Article Herpes simplex virus-1 and cytomegalovirus DNAs detection in the inner ear of implanted patients with non-congenital infection. 2017

Di Nardo, Walter / Anzivino, Roberta / Cattani, Paola / Santangelo, Rosaria / De Corso, Eugenio / Paludetti, Gaetano. ·a Department of Head and Neck Surgery, Institute of Otorhinolaryngology , Catholic University of Sacred Heart , Rome , Italy. · b Department of Diagnostic and Laboratory Medicine, Institute of Microbiology , Catholic University of Sacred Heart , Rome , Italy. ·Acta Otolaryngol · Pubmed #28332898.

ABSTRACT: CONCLUSIONS: The detection of cytomegalovirus (CMV) and herpes simplex virus-1 (HSV-1) genome in perilymph of patients with negative serology or clinical history for congenital infections supports the hypothesis that Herpesviridae, even after acquired postnatal infections, could remain in latent phase in the spiral ganglion and damage the cochlea by a possible subsequent reactivation. Further studies are needed to identify the markers of such reactivation. OBJECTIVE: To identify the presence of certain viral species in the endolabyrinthic fluid of deaf patients with non-congenital infection. The research of viral DNA within the inner ear is the only direct way to increase our knowledge about the viral role in postnatal damage to the cochlea. METHODS: Thirty-six patients (1-69 years) suffering from bilateral sensorineural hearing loss (SNHL) were subjected, during cochlear implant (CI) surgery, to a sample taking of inner ear fluid. Several types of viral genome (HSV, VZV, CMV, EBV and Enterovirus) were investigated in each sample through multiplex polymerase chain reaction (PCR) and reverse transcriptase-polymerase chain reaction (RT-PCR). Radiological exams, serology (specific IgG and IgM) and PCR of peripheral blood were also performed. RESULTS: While the research of the viral genome in peripheral blood was negative in all patients, multiplex PCR on endolabyrinthic fluid samples was positive in three patients (two cases of CMV-DNA and one case of HSV-1 DNA).

5 Article Improvement of telephone communication in elderly cochlear implant patients. 2014

Di Nardo, Walter / Anzivino, Roberta / Gambini, Gloria / De Corso, Eugenio / Paludetti, Gaetano. ·Institute of Otorhinolaryngology, Catholic University of the Sacred Heart, Rome, Italy. ·Audiol Neurootol · Pubmed #25733363.

ABSTRACT: INTRODUCTION: Elderly patients demonstrate more difficulty in telephone communication than in direct conversation. This deterioration in comprehension is due most likely to the narrowing of frequency range of transmission (300-3,400 Hz) and the lack of specific maps in the sound processor to accommodate the reduced information. AIMS: The goal of this study was to create a new 'telephone map' specific for phone use and to verify its effectiveness even in elderly patients. METHODS: Twenty cochlear implant (CI) adult patients divided into two age groups (under 60 and over 60 years) were included in the study. All patients were assessed with a word recognition test presented via recorded, conventional telephone-transmitted voice signal while using their everyday map (SB-map) and while using the experimental map (T-map). The latter was created by lowering the current level to the minimum value for electrodes representing frequencies outside the range of the telephone signal without changing the frequency bands assigned to them. RESULTS: In experimental listening conditions, the average recognition score using the SB-map was 65.5% in patients under 60 and 36.5% in patients over 60, while using the T-map it was 73.5 and 41.5%, respectively. This difference between the two maps was statistically significant in both groups (p ˂ 0.05) and was confirmed by subjective assessment. After 3 months of training provided to the over 60 CI group, subjects showed further improvement. DISCUSSION: The increase in comprehension skills by phone-transmitted speech with the T-map is objective and immediate in both groups of patients and proves to be improved further after training. The results demonstrate that it is possible to reduce the background noise and improve the ability to comprehend the phone message through changes to some map parameters. CONCLUSIONS: In light of the results obtained, we believe that our experimental map, applicable to all types of implants, currently represents a simple and effective solution to improve telephone communication in patients with CI.