Pick Topic
Review Topic
List Experts
Examine Expert
Save Expert
  Site Guide ··   
Cat-Scratch Disease HELP
Based on 362 articles published since 2009

These are the 362 published articles about Cat-Scratch Disease that originated from Worldwide during 2009-2019.
+ Citations + Abstracts
Pages: 1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15
1 Editorial Limping in children: look what the cat dragged in! 2019

Chantrain, Christophe F / Genin, Caroline. ·Paediatric Haematology Oncology, Department of Paediatrics, Centre Hospitalier Chrétien (CHC), Clinique de l'Espérance, Liège, Belgium. · Pediatric Infectious Disease, Department of Paediatrics, Centre Hospitalier Chrétien (CHC), Clinique de l'Espérance, Liège, Belgium. ·Arch Dis Child · Pubmed #29959127.

ABSTRACT: -- No abstract --

2 Review Neuroretinitis: a review. 2018

Abdelhakim, Aliaa / Rasool, Nailyn. ·Department of Ophthalmology, Edward Harkness Eye Institute, Columbia University, New York, New York, USA. ·Curr Opin Ophthalmol · Pubmed #30148725.

ABSTRACT: PURPOSE OF REVIEW: Neuroretinitis is an inflammatory disorder of the eye presenting with optic disc edema and the delayed development of a macular star secondary to optic nerve swelling toward the macular structures. Neuroretinitis can be divided into idiopathic, infectious (including neuroretinitis associated with cat scratch disease) and recurrent. RECENT FINDINGS: The clinical presentation of neuroretinitis includes impaired visual acuity, dyschromatopsia, relative afferent pupillary defects and visual field abnormalities - particularly cecocentral and central scotomas. Features suggesting recurrent neuroretinitis include poorer visual recovery and visual field abnormalities representing damage to greater parts of the optic nerve. Treatment of neuroretinitis is based upon the cause of the disease. Specifically, in patients with cat scratch neuroretinitis, visual recovery is often favorable regardless of treatment with medication. However, some authors favor treatment with antibiotics early in the course of disease to limit progression and ensure eradication of the organism. SUMMARY: Neuroretinitis can result from a number of infectious and noninfectious causes and it is essential that clinicians recognize the disease and determine the underlying etiology to ensure the best possible treatment and visual prognosis for the patient.

3 Review Ocular manifestations of bartonellosis. 2018

Mabra, Dawn / Yeh, Steven / Shantha, Jessica G. ·Morehouse School of Medicine. · Emory Eye Center, Emory University School of Medicine, Atlanta, Georgia, USA. ·Curr Opin Ophthalmol · Pubmed #30124532.

ABSTRACT: PURPOSE OF REVIEW: To review the systemic and ocular complications of Bartonella spp. infections specifically cat scratch disease, encompassing epidemiology, laboratory diagnostics, ophthalmic imagining, and treatment. RECENT FINDINGS: Recent studies have shown that ocular manifestations occur in approximately 4.4% of cat scratch disease patients. The annual prevalence is lower than previously reported to be approximately 12 500 cases annually. Mainstay treatment continues to be oral antibiotics with and without corticosteroids and is dependent on associated systemic manifestations, age, and patient immune status. More recently anti-VEGF agents have been used for complications such as cystoid macular edema and choroidal neovascularization. SUMMARY: Bartonella spp. infections continue to be a common cause uveitis with ophthalmic manifestations ranging from neuroretinits, vascular occlusions, to choroidal granulomas. Review of associated risk factors including contact with feline reservoirs will aid in recognition and diagnosis of this disease entity. Laboratory diagnostics continue to improve to help with the diagnosis of this entity.

4 Review Ophthalmic manifestations of bartonella infection. 2017

Amer, Radgonde / Tugal-Tutkun, Ilknur. ·aDepartment of Ophthalmology, Hadassah Medical Center, Jerusalem bDepartment of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey. ·Curr Opin Ophthalmol · Pubmed #28984726.

ABSTRACT: PURPOSE OF REVIEW: The eye is commonly affected in disseminated cat scratch disease (CSD) caused by Bartonella species. This article reviews recently published data on epidemiology of CSD, clinical features of ocular involvement, diagnosis and treatment. RECENT FINDINGS: The annual incidence of CSD has been estimated as 4.7 per 100 000 in the United States. It occurs predominantly in the southern states, with a peak in January, and disproportionately affects children. Retinal infiltrates, neuroretinitis and branch retinal artery occlusions have been reported as common manifestations of ocular bartonellosis in recent series. The use of different antigens for serodiagnosis and new real-time PCR assays for molecular diagnosis have been described. Despite lack of a standard treatment, good visual outcomes were generally reported in patients with ocular bartonellosis. SUMMARY: Bartonella infections continue to be a burden worldwide and epidemiologic features may guide preventive measures in high-risk regions and populations. An increased awareness of diverse posterior segment manifestations will lead to an early diagnosis of ocular bartonellosis. Laboratory diagnostic methods continue to evolve and may be applied to the investigation of ocular fluids for a definitive diagnosis of ocular bartonellosis. Well designed clinical trials are required to establish the optimum treatment of especially sight-threatening manifestations.

5 Review Bartonellosis in Chronic Kidney Disease: An Unrecognized and Unsuspected Diagnosis. 2017

Shamekhi Amiri, Fateme. ·Division of Nephrology, Imam Khomeini Hospital, Faculty of Medicine, National Tehran University of Medical Sciences, Tehran, Iran. ·Ther Apher Dial · Pubmed #28884961.

ABSTRACT: Systemic cat scratch disease or bartonellosis is a clinical entity caused by Bartonella henselae, which manifests with necrotizing granulomas in visceral organs. The cat flea, Ctenocephalides felis, is the vector responsible for horizontal transmission of the disease from cat to cat, and its bite can also infect humans. In immunocompromised patients including chronic kidney disease and renal transplant recipients, it can cause persistent and disseminated cat scratch disease. The aim of this paper is to perform a systematic review of the studies that have addressed the diagnostic methods of cat scratch disease in chronic kidney disease and renal transplant recipients. This review was searched via electronic PubMed and Google scholar databases. Few qualitative full-text original articles in chronic kidney disease and kidney transplant were extracted. At this paper, 19 articles identified including six articles in chronic kidney disease and 13 articles in renal transplant recipients. Of these six identified case reports in chronic kidney disease, serology via immunofluorescence antibody test was led to diagnosis of cat scratch disease in five patients and a one patient showed nonreactive serologic test. Polymerase chain reaction usage to detect deoxyribonucleic acid in tissue biopsy and bone marrow biopsy was led to diagnosis. Cat scratch disease diagnosis in 13 renal transplant recipients was attained more by combining serology and polymerase chain reaction to detect deoxyribonucleic acid in tissue specimens. These selected studies demonstrate that serology and polymerase chain reaction via deoxyribonucleic acid extraction of tissue specimens yield the best outcome in diagnostic field of bartonellosis.

6 Review [Cat scratch disease - a neglected zoonosis]. 2017

Hozáková, L / Rožnovský, L / Janout, V. · ·Epidemiol Mikrobiol Imunol · Pubmed #28691834.

ABSTRACT: Cat scratch disease is a relatively rare infection that is caused by the bacterium Bartonella henselae. This disease occurs after cat scratch or bite. The course of the disease depends on the patients immunity status. In immunocompetent patients, the disease typically runs as a lymph node syndrome. Sometimes, mild general symptoms may appear, or the course can be atypical with a more serious clinical manifestation involving various organs. In immunocompromised patients, Bartonella henselae can cause bacillary angiomatosis or peliosis with a severe course.

7 Review [Osteomyelitis in cat scratch disease: A case report and literature review]. 2016

Lafenetre, M / Herbigneaux, R M / Michoud, M / Descours, G / Debillon, T. ·Hôpital Couple-Enfant-Grenoble, avenue Maquis-du-Grésivaudan, 38700 La Tronche, France. Electronic address: marie.lafenetre@gmail.com. · Service de pédiatrie, hôpital de Chambéry, place Lucien-Biset, 73000 Chambéry, France. · Service de radiologie, hôpital de Chambéry, place Lucien-Biset, 73000 Chambéry, France. · Laboratoire de bactériologie, centre de biologie Est, centre hospitalier Lyon Est, 59, boulevard Pinel, 69677 Bron cedex, France. · Service de réanimation néonatale, hôpital Couple-Enfant-Grenoble, avenue Maquis-du-Grésivaudan, 38700 La Tronche, France. ·Arch Pediatr · Pubmed #26727156.

ABSTRACT: INTRODUCTION: Cat scratch disease is an infection caused by Bartonella henselae. The main clinical form is a lymphadenopathy with fever. However, uncommon bone involvement has been described. CASE REPORT: In this paper, we report a case of osteomyelitis in a 13-year-old teenager infected with B. henselae. The diagnosis was made based on PCR only because the serology was negative. A literature review reports 65 cases of osteomyelitis due to cat scratch disease. For each case, serology and PCR were notified. CONCLUSION: Osteomyelitis caused by B. henselae is a rare clinical manifestation. The diagnosis can be difficult, but the medical history must be accurate to search for contact with a cat and a cat scratch.

8 Review Disseminated cat-scratch disease: case report and review of the literature. 2016

Chang, Chih-Chen / Lee, Chia-Jie / Ou, Liang-Shiou / Wang, Chao-Jan / Huang, Yhu-Chering. ·a Department of Medical Imaging and Intervention , Chang Gung Memorial Hospital , Linkou , Taiwan. · b Department of Pediatrics , Chang Gung Memorial Hospital , Linkou , Taiwan. · c Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics , Chang Gung Memorial Hospital , Linkou , Taiwan. · d Chang Gung University College of Medicine , Kweishan, Taoyuan , Taiwan. ·Paediatr Int Child Health · Pubmed #25940800.

ABSTRACT: Cat scratch disease (CSD) can present as a systemic disease in 5-10% of cases and lead to various disease entities. A previously healthy 16-month-old boy presented with fever for 7 days without other obvious symptoms. Abdominal computed tomography scan demonstrated enlarged right inguinal lymph nodes and multiple small round hypodensities in the spleen. Despite antibiotic treatment for 1 week, the fever persisted and the intrasplenic lesions progressed. Inguinal lymph node biopsy confirmed CSD by immunohistochemistry staining. The diagnosis of CSD was also supported by a history of contact, imaging and serological findings. The patient recovered after treatment with azithromycin for a total of 5 weeks and, in serial follow-up, the hepatosplenic micro-abscesses resolved after 4th months.

9 Review Evaluation of Cat Scratch Disease Cases Reported from Turkey between 1996 and 2013 and Review of the Literature. 2015

Uluğ, Mehmet. ·Department of Infectious Diseases and Clinic Microbiology, Private Ümit Hospital, Eskişehir, Turkey. ·Cent Eur J Public Health · Pubmed #26851430.

ABSTRACT: BACKGROUND: Cat scratch disease (CSD), the most common cause of chronic lymphadenopathy among children and adolescents, typically features regional lymphadenitis associated with inoculation site due to a cat scratch or bite. OBJECTIVE: The aim of this study was to systematically review the articles related to CSD which were reported from Turkey in national and international journals in the last 18 years with a pooled-analysis method. METHODS: The articles related to CSD were retrieved by search of four national (Ulakbim Turkish Medical Literature Databases) and three international databases (Pub-Med, Science Citation Index (SCI) and Google scholar). RESULTS: Between the years 1996-2013, CSD cases have been published in a total of 16 articles (4 international, 12 national). These articles which were presented as a case report included a total of 18 CSD cases (38.8% women, 61.2% men; median age 16 years). The most common clinicopathologic subtypes of CSD are regional lymphadenitis (n=9), hepatosplenic (n=3) and neuroretinitis (n=2). The most common complaints of patients were swelling (94.4%), fever (61.2%) and weakness (50%) at admission. On exam, the most common signs were lymphadenopathy (94.4%), fever (61.2%), splenomegaly (16.6%), and skin eruption (16.6%). CONCLUSION: This pooled analysis which enabled the evaluation of a large number of CSD cases, indicated that careful evaluation of clinical findings and histopathological investigation will provide valuable support for diagnosis and treatment of CSD.

10 Review Cat-Scratch Disease: Case Report and Review of the Literature. 2015

Gai, M / d'Onofrio, G / di Vico, M C / Ranghino, A / Nappo, A / Diena, D / Novero, D / Limerutti, G / Messina, M / Biancone, L. ·Nephrology, Dialysis, and Transplantation Unit, University of Torino-AOU Città della Salute e della Scienza di Torino, Molinette, Italy. Electronic address: massimogai@gmail.com. · Nephrology and Dialysis Unit, "Magna Graecia" University of Catanzaro, Catanzaro, Italy. · Nephrology, Dialysis, and Transplantation Unit, University of Torino-AOU Città della Salute e della Scienza di Torino, Molinette, Italy. · Anatomic Pathology 2 Unit, University of Torino-AOU Città della Salute e della Scienza di Torino, Molinette, Italy. · Radiology Unit, AOU Città della Salute e della Scienza di Torino, Molinette, Italy. ·Transplant Proc · Pubmed #26361690.

ABSTRACT: Cat-scratch disease (CSD) is caused by Bartonella henselae and characterized by self-limited fever and granulomatous lymphadenopathy. In some cases signs of a visceral, neurologic, and ocular involvement can also be encountered. In this report we describe the development of CSD in a kidney transplant patient. Immunocompromised hosts are more susceptible to infection from Bartonella compared with the standard population. Infection of Bartonella should be considered as a differential diagnosis in kidney transplant patients with lymphadenopathy of unknown origin.

11 Review Ocular bartonellosis in transplant recipients: two case reports and review of the literature. 2015

Lee, R A / Ray, M / Kasuga, D T / Kumar, V / Witherspoon, C D / Baddley, J W. ·Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. · Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama, USA. · Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. · Birmingham Veterans Affairs Medical Center, Birmingham, Alabama, USA. ·Transpl Infect Dis · Pubmed #26146758.

ABSTRACT: Cat scratch disease is caused by Bartonella henselae and usually manifests as localized lymphadenopathy and fever in immunocompetent patients. Immunocompromised patients are at risk for developing disseminated disease affecting the liver, spleen, eyes, central nervous system, and other organs. Bartonellosis is infrequently reported in solid organ transplant recipients, and published case reports usually discuss disseminated infection. Localized ocular disease with B. henselae, while well documented in immunocompetent hosts, is uncommon in immunocompromised patients. Herein, we present 2 cases of ocular bartonellosis in renal transplant patients, 1 with disseminated infection, and 1 without.

12 Review [Diagnosis of infectious lymphadenitis]. 2015

Melenotte, C / Edouard, S / Lepidi, H / Raoult, D. ·Faculté de médecine, URMITE, UM63, CNRS 7278, IRD198, Inserm 1095, Aix Marseille université, 27, boulevard Jean-Moulin, 13385 Marseille cedex 5, France. · Faculté de médecine, URMITE, UM63, CNRS 7278, IRD198, Inserm 1095, Aix Marseille université, 27, boulevard Jean-Moulin, 13385 Marseille cedex 5, France. Electronic address: didier.raoult@gmail.com. ·Rev Med Interne · Pubmed #26021493.

ABSTRACT: Adenitis is a common disorder requesting numerous medical specialties. Etiologies are dominated by viral and bacterial infections, and more rarely parasitic, or by neoplastic and inflammatory diseases. Nevertheless, etiology remains often unknown and invasive tests may be required. On nodal tissue sample, histological examination, culture and polymerase chain reaction (PCR) are realized. PCR has revolutionized the diagnostic approach and consequently, knowledge of infectious lymphadenopathy. Previously, staphylococcus, streptococcus and mycobacterium were the main infectious agents identified in lymph nodes. Since its use, new emergent microorganisms responsible of lymphadenitis have been identified. Bartonella henselae, responsible of cat scratch disease, is to date the infectious agent most often encountered in adenitis. Mycobacterium avium subsp. hominisuis has been recently described as responsible of children lymphadenitis. PCR has become an essential tool in the diagnostic process of infectious lymphadenitis. Here, we propose a literature review on infectious adenitis and we emphasize the diagnostic strategy of adenitis.

13 Review Update and Commentary on Four Emerging Tick-Borne Infections: Ehrlichia muris-like Agent, Borrelia miyamotoi, Deer Tick Virus, Heartland Virus, and Whether Ticks Play a Role in Transmission of Bartonella henselae. 2015

Wormser, Gary P / Pritt, Bobbi. ·Division of Infectious Diseases, New York Medical College, 40 Sunshine Cottage Road, Skyline Office #2N-C20, Valhalla, NY 10595, USA. Electronic address: gwormser@nymc.edu. · Division of Clinical Microbiology, Department of Pathology and Laboratory Medicine, Mayo Clinic, 200 1st Street, SW, Rochester, MN 55905, USA. ·Infect Dis Clin North Am · Pubmed #25999230.

ABSTRACT: Emerging tick-borne infections continue to be observed in the United States and elsewhere. Current information on the epidemiology, clinical and laboratory features, and treatment of infections due to Ehrlichia muris-like agent, deer tick virus, Borrelia miyamotoi sensu lato, and Heartland virus was provided and critically reviewed. More research is needed to define the incidence and to understand the clinical and the laboratory features of these infections. There is also a growing need for the development of sensitive and specific serologic and molecular assays for these infections that are easily accessible to clinicians.

14 Review Clinicocytopathologic correlation in an atypical presentation of lymphadenopathy with review of literature. 2015

Choi, Alexander H / Bolaris, Michael / Nguyen, Diana K / Panosyan, Eduard H / Lasky, Joseph L / Duane, Gloria B. ·From the Departments of Pathology and choi.alexander7@gmail.com. · Pediatrics, Los Angeles County-Harbor-UCLA Medical Center, Los Angeles, CA. · From the Departments of Pathology and. ·Am J Clin Pathol · Pubmed #25873511.

ABSTRACT: OBJECTIVES: To present a clinicocytopathologic correlation of an atypical case of cat scratch disease (CSD) involving retroperitoneal lymph nodes, with emphasis on communication between service teams for managing lymphadenopathy of unknown origin. We consider clinical and cytologic differential diagnoses and review the literature on atypical cases of CSD, with emphasis on abdominal presentation and cytologic findings. METHODS: Clinical services met with the cytology service to review clinical and pathologic features. Literature was reviewed via PubMed search (Harbor-UCLA subscriptions). Immunohistochemistry and Steiner silver stains were performed by Harbor-UCLA Department of Pathology. Enzyme-linked immunosorbent assay IgG and IgM Bartonella henselae titers were carried out by Quest Nichols Institute. RESULTS: Fine-needle aspirate Diff-Quik and Papanicolaou smears and H&E-stained cell block showed abundant histiocytes, monocytoid B cells, and numerous neutrophils associated with necrosis corresponding to a late stage of CSD infection. Silver stain was positive for clumps of pleomorphic organisms. IgM and IgG antibody titers were elevated. CONCLUSIONS: The cytologic findings of CSD in an atypical abdominal presentation are similar to those of a classic presentation. Laboratory workup for atypical CSD should include at least two other modalities aside from cytomorphologic features. Close clinical and cytologic correlation avoided potentially unnecessary and harmful surgery and enabled timely treatment.

15 Review Cat scratch disease during infliximab therapy: a case report and literature review. 2015

Zhou, Yi / Yin, Geng / Tan, Chunyu / Liu, Yi. ·Department of Rheumatology, West China Hospital, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, Sichuan, China. ·Rheumatol Int · Pubmed #25547623.

ABSTRACT: Cat scratch disease may occur during etanercept therapy, but there has been no report on infliximab-associated cat scratch disease. We report a case of a 23-year-old woman who developed right inguinal lymph node enlargement following a cat scratch. The patient had received infliximab therapy for spondyloarthropathy. She was successfully managed by discontinuing infliximab and by treatment with moxifloxacin and amikacin.

16 Review Cat-scratch fever and lymphadenopathy in a rheumatoid arthritis patient on tocilizumab. 2015

Singh, Namrata / Sinclair, Lori L / IJdo, Jacob. ·From the University of Iowa Hospitals and Clinics, Iowa City, IA. ·J Clin Rheumatol · Pubmed #25539435.

ABSTRACT: -- No abstract --

17 Review Cat scratch disease of the eye: a case report and literature review. 2014

Alaan, Kristina / Fisher, Melanie / Ellis, Brian. · ·W V Med J · Pubmed #25643469.

ABSTRACT: This is the case of a middle-aged male with no other medical issues who presented with acute, unilateral visual disturbance. In lieu of specific ophthalmologic findings, his age and presentation, he was treated for presumed inflammatory process. It was only after steroids and the results of serological testing that an infectious agent was determined. He was eventually diagnosed with ocular Bartonellosis. He was treated with oral doxycycline and rifampin and slowly improved. The thesis of this case report is that a thorough history prior to rapid and somewhat presumptive treatment may have prevented unnecessary immunosuppression and delay in appropriate antimicrobial therapy.

18 Review Hepatosplenic cat scratch disease in immunocompetent adults: report of 3 cases and review of the literature. 2014

García, Juan C / Núñez, Manuel J / Castro, Begoña / Fernández, Jesús M / López, Asunción / Portillo, Aránzazu / Oteo, José A. ·Servicio de Medicina Interna (JCG, MJN), Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Galicia · Servicio de Medicina Interna (BC, JMF), Hospital Comarcal del Salnés, Vilagarcía de Arousa, Pontevedra, Galicia · Servicio de Medicina Interna (AL), Complejo Hospitalario Universitario de Ourense, Ourense, Galicia · Departamento de Enfermedades Infecciosas (AP, JAO), Hospital San Pedro-CIBIR, Logroño, La Rioja, Spain. ·Medicine (Baltimore) · Pubmed #25398062.

ABSTRACT: Cat-scratch disease (CSD) is the most frequent presentation of Bartonella henselae infection. It has a worldwide distribution and is associated with a previous history of scratch or bite from a cat or dog. CSD affects children and teenagers more often (80%) than adults, and it usually has a self-limiting clinical course. Atypical clinical course or systemic symptoms are described in 5%-20% of patients. Among them, hepatosplenic (HS) forms (abscess) have been described. The majority of published cases have affected children or immunosuppressed patients. Few cases of HS forms of CSD in immunocompetent adult hosts have been reported, and data about the management of this condition are scarce. Herein, we present 3 new cases of HS forms of CSD in immunocompetent adults and review 33 other cases retrieved from the literature. We propose an approach to clinical diagnosis and treatment with oral azithromycin.

19 Review [Bartonella henselae infection-cat-scratch disease in children (case report)]. 2014

Anonymous1690806. · ·Georgian Med News · Pubmed #25214279.

ABSTRACT: This study was designed to investigate the 11 year old patient with cat scratch disease. The diagnoes of this infection was based on detailed history, physical examenination and para-clinical data analyses. In case of cat-scratch disease (because it is rare diagnosis), a different approach is required to every specific occaison. A series of investigations (most informative is intrinsic factor antibody - IFA) should be conducted to determain the cat-scratch disease from the various reasons of the lymphocytic leukaemoid reaction.

20 Review Visceral cat scratch disease with endocarditis in an immunocompetent adult: a case report and review of the literature. 2014

Shasha, David / Gilon, Dan / Vernea, Fiona / Moses, Allon E / Strahilevitz, Jacob. ·1 The Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center , Jerusalem, Israel . ·Vector Borne Zoonotic Dis · Pubmed #24575798.

ABSTRACT: Infective endocarditis and hepatosplenic abscesses are rare manifestations of cat scratch disease (CSD), especially among immunocompetent adults. An otherwise healthy woman who presented with fever and abdominal pain was diagnosed with multiple abscesses in the spleen and the liver, as well as a mitral valve vegetation. PCR on spleen tissue was positive for Bartonella henselae. Prolonged treatment with doxycycline and gentamicin led to complete recovery. Review of the literature revealed 18 cases of hepatosplenic CSD in immunocompetent adults; the majority presented with fever of unknown origin and abdominal pain. In most cases the causative organism was B. henselae and the pathological findings were necrotizing granulomas, similar to the pathological features in classic CSD. Concomitant endocarditis was diagnosed in one case. Because Bartonella is one of the leading pathogens of culture-negative endocarditis, we raise the question of whether a comprehensive evaluation for endocarditis is needed in cases of systemic CSD.

21 Review Cat-scratch disease. 2014

Biancardi, Ana Luiza / Curi, Andre Luiz Land. ·Fundação Oswaldo Cruz , Rio de Janeiro , Brazil. ·Ocul Immunol Inflamm · Pubmed #24107122.

ABSTRACT: PURPOSE: To discuss the systemic and ocular manifestations, diagnosis and treatment of Bartonella infection. METHOD: Review of the literature. RESULTS: Bartonella are facultative intracellular Gram-negative rods that infect the erythrocytes or endothelial cells and are related to cat scratch disease (CSD). Bartonella henselae infection has localized or systemic features; the ocular diseases related to Bartonella affect 5--10% of patients with CSD. The diagnosis is based on clinical findings and laboratory tests. The indication of antibiotic therapy depends on the manifestation of the Bartonella infection, the host immunity and the patient's age. CONCLUSION: Physicians should look for Bartonella henselae in cases of follicular conjuntivitis and regional limphadenopathy, neuroretinitis or retinal infiltrates; currently, serological tests can confirm the clinical suspicion of this infection.

22 Review Cat-scratch disease during anti-tumor necrosis factor-alpha therapy: case report and review of the literature. 2014

Osório, Filipa / Pedrosa, Ana / Azevedo, Filomena / Figueiredo, Paulo / Magina, Sofia. ·Department of Dermatology and Venereology, Centro Hospitalar de São João EPE, Porto, PortugalDepartment of Infectious Diseases, Centro Hospitalar de São João EPE, Porto, PortugalDepartment of Pharmacology and Therapeutics, Faculty of Medicine of University of Porto, Porto, Portugal. ·Int J Dermatol · Pubmed #23557494.

ABSTRACT: -- No abstract --

23 Review Arthropod-borne bacterial diseases in pregnancy. 2013

Dotters-Katz, Sarah K / Kuller, Jeffrey / Heine, R Phillips. ·Resident, Duke University. · Professor of Obstetrics and Gynecology. · Associate Professor of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Duke University Medical Center, Durham, NC. ·Obstet Gynecol Surv · Pubmed #25102120.

ABSTRACT: Arthropod-borne bacterial diseases affect more than 25,000 Americans every year and thousands more around the world. These infections present a diagnostic dilemma for clinicians because they mimic many other pathologic conditions and are often low on or absent from the differential diagnosis list. Diagnosis is particularly challenging during pregnancy, as these infections may mimic common pregnancy-specific conditions, such as typical and atypical preeclampsia, or symptoms of pregnancy itself. Concerns regarding the safety in pregnancy of some indicated antibiotics add a therapeutic challenge for the prescriber, requiring knowledge of alternative therapeutic options for many arthropod-borne bacterial diseases. Physicians, especially those in endemic areas, must keep this class of infections in mind, particularly when the presentation does not appear classic for more commonly seen conditions. This article discusses presentation, diagnosis, and treatment of the most common of these arthropod-borne bacterial diseases, including Lyme disease, Rocky Mountain spotted fever, tick-borne relapsing fever, typhus, plague, cat-scratch disease, and Carrión disease.

24 Review Cat-scratch disease presenting as a solitary splenic abscess in an immunocompetent adult: case report and literature review. 2013

Anyfantakis, Dimitrios / Kastanakis, Miltiades / Papadomichelakis, Alexandros / Petrakis, Georgios / Bobolakis, Emmanouil. ·Primary Health Care Centre of Kissamos, Crete, Greece. danyfantakis@med.uoc.gr ·Infez Med · Pubmed #23774977.

ABSTRACT: Cat-scratch disease is a common zoonotic infectious disease caused by Bartonella henselae. It is generally characterized by regional lymphadenopathy following exposure to an infected cat. Organ systemic manifestations occur rarely in atypical forms of the disease. Abscess of the spleen represents a rare, life-threatening clinical entity. Here we report an unusual case of cat scratch disease presenting as an isolated splenic abscess in an immunocompetent adult. Comprehensive social history revealed retrospectively close contact with cats. Diagnosis of B. henselae infection was confirmed on the basis of positive serology, skin lesion and imaging findings. Initial efforts at spleen preserving management failed to improve clinical symptoms and classical splenectomy was finally performed. Splenic bartonellosis may become potentially fatal if not recognized. Since diagnosis is challenging, a high index of clinical suspicion is required.

25 Review Cat scratch disease and other Bartonella infections. 2013

Zangwill, Kenneth M. ·Pediatric Infectious Diseases, David Geffen School of Medicine at UCLA, Harbor-UCLA Medical Center, Los Angeles, USA. kzangwill@uclacvr.labiomed.org ·Adv Exp Med Biol · Pubmed #23654065.

ABSTRACT: First described in 1931, cat scratch disease remains the most commonly identified clinical syndrome associated with Bartonella infection. Over the last 20 years, however, the discovery and use of modern diagnostic tests has greatly expanded our understanding of the pathogenesis, clinical spectrum, and treatment options for Bartonella infections of all types. Indeed, each varies substantially depending on the infecting species and the immune status of the host.